Reply to "heparan sulfate in baculovirus binding and entry of Mammalian cells".

نویسندگان

  • K-E Makkonen
  • P Turkki
  • J P Laakkonen
  • S Ylä-Herttuala
  • V Marjomäki
  • K J Airenne
چکیده

K.-E. Makkonen, P. Turkki, J. P. Laakkonen, S. Ylä-Herttuala, V. Marjomäki, K. J. Airenne A. I. Virtanen Institute, Department of Biotechnology and Molecular Medicine, University of Eastern Finland, Kuopio, Finland; Department of Biological and Environmental Science, Division of Cell and Molecular Biology/Nanoscience Center, University of Jyväskylä, Jyväskylä, Finland; Gene Therapy Unit, Kuopio University Hospital, Kuopio, Finland; Research Unit, Kuopio University Hospital, Kuopio, Finland

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Heparan sulfate in baculovirus binding and entry of mammalian cells.

Makkonen and his colleagues published an article in the Journal of Virology entitled “6-Oand N-Sulfated Syndecan-1 Promotes Baculovirus Binding and Entry into Mammalian Cells” (1). Some parts of the data and conclusions seem misleading and not fully justified. Heparan sulfate (HS) alone can bind baculovirus to cells during entry and transduction. Syndecan-1 (SDC-1) contains a protein core and H...

متن کامل

Interaction of herpes simplex virus glycoprotein gC with mammalian cell surface molecules.

The entry of herpes simplex virus (HSV) into mammalian cells is a multistep process beginning with an attachment step involving glycoproteins gC and gB. A second step requires the interaction of glycoprotein gD with a cell surface molecule. We explored the interaction between gC and the cell surface by using purified proteins in the absence of detergent. Truncated forms of gC and gD, gC1(457t),...

متن کامل

A heparin-binding activity on Leishmania amastigotes which mediates adhesion to cellular proteoglycans

The intracellular amastigote form of leishmania is responsible for the cell-to-cell spread of leishmania infection in the mammalian host. In this report, we identify a high-affinity, heparin-binding activity on the surface of the amastigote form of leishmania. Amastigotes of Leishmania amazonensis bound approximately 120,000 molecules of heparin per cell, with a Kd of 8.8 x 10(-8) M. This hepar...

متن کامل

Heparan Sulfate-Dependent Enhancement of Henipavirus Infection

UNLABELLED Nipah virus and Hendra virus are emerging, highly pathogenic, zoonotic paramyxoviruses that belong to the genus Henipavirus. They infect humans as well as numerous mammalian species. Both viruses use ephrin-B2 and -B3 as cell entry receptors, and following initial entry into an organism, they are capable of rapid spread throughout the host. We have previously reported that Nipah viru...

متن کامل

A Novel Role for 3-O-Sulfated Heparan Sulfate in Herpes Simplex Virus 1 Entry

Herpes simplex virus type 1 (HSV-1) binds to cells through interactions of viral glycoproteins gB and gC with heparan sulfate chains on cell surface proteoglycans. This binding is not sufficient for viral entry, which requires fusion between the viral envelope and cell membrane. Here, we show that heparan sulfate modified by a subset of the multiple D-glucosaminyl 3-O-sulfotransferase isoforms ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of virology

دوره 88 8  شماره 

صفحات  -

تاریخ انتشار 2014